Omeprazole, sold under the brand names Prilosec and Losec among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome.
Facts
Mechanism of ActionIrreversibly blocks the H+/K+-ATPase enzyme system on gastric parietal cells, inhibiting the final step of stomach acid secretion. 1 Approved UseTreats gastroesophageal reflux disease (GERD), peptic ulcer disease and Zollinger-Ellison syndrome. 1 First Approved / Isolated Year Significant RiskNausea, headaches and abdominal pain; serious risks include Clostridioides difficile colitis, increased pneumonia risk, bone fracture risk and masking of stomach cancer. 1 Classification
Approval Status ATC ClassSourced to the subject's own accountA: Alimentary Tract and Metabolism 2 Route of Administration WHO Essential MedicineSourced to the subject's own account Connections
Treats
Source Omeprazole (Wikipedia)
Sources
1. Omeprazole (Wikipedia)
Wikimedia FoundationLead section
gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome
Infobox, drug class
Proton-pump inhibitor
Mechanism of action section
irreversibly blocks the H+/K+-ATPase enzyme system
History section
1988
Adverse effects section
Serious side effects may include Clostridioides difficile colitis
Lead section, route-of-administration statement
It can be taken by mouth or by injection into a vein.
- Regulatory approval status
View the Source 2. Anatomical Therapeutic Chemical Classification System (Wikipedia)
WikipediaFirst-level anatomical group codes, Code AQuote, First-level anatomical group codes, Code A
Alimentary tract and metabolism
3. WHO Model List of Essential Medicines (Wikipedia)
WikipediaWHO Model List of Essential Medicines, Antiulcer medicines sectionQuote, WHO Model List of Essential Medicines, Antiulcer medicines section
Omeprazole
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