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Condition

Polycystic Ovary Syndrome

Endocrine, Nutritional and Metabolic Diseases

Polycystic ovary syndrome is an endocrine disorder affecting people with ovaries during their reproductive years. It is characterized by some combination of irregular or absent menstrual periods, elevated androgen levels, and multiple small follicles on the ovaries. Its exact cause is not fully understood, though genetic and metabolic factors, including insulin resistance, are thought to contribute.

Facts
Classification
Body System
Endocrine System 1
ICD-10 Chapter
IV: Endocrine, Nutritional and Metabolic Diseases 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 2
Condition Class
Endocrine (hormonal) disorder 4
First Described
1935 4
Prevalence
Between 5% and 18% of women 4
Causative Agent
Causative Agent (category)
Genetic / Hereditary 3
Causative Agent (category)
Idiopathic / Multifactorial 3
Polycystic Ovary Syndrome
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Connections

Associated With

Endocrinology, Medical Specialties

PCOS is a hormonal/endocrine disorder of the ovaries; standard specialty is endocrinology (also managed by obstetrics-and-gynecology, endocrinology chosen as the primary systemic classification).

Treated By

Metformin is commonly used off-label to manage insulin resistance in PCOS.

Source Metformin (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IV
Quote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
View the Source
2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health Organization
  • Lead section, transmission-route statement (inferred from disease-category)
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
  • Main Types section
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
View the Source
3. Polyendocrine metabolic ovarian syndrome (Wikipedia)
infobox causes
Quote, infobox causes
causes: Genetic and environmental factors
View the Source
4. Wikipedia: Polycystic ovary syndrome
  • Lead section, first sentence
    Polyendocrine metabolic ovarian syndrome (PMOS), previously called polycystic ovary syndrome (PCOS), is the most common hormonal disorder in women of reproductive age.
  • History section
    In 1935, American gynecologists Irving F. Stein and Michael L. Leventhal published a report linking polycystic ovaries to hirsutism, infertility, and lack of periods.
  • Epidemiology section
    PMOS occurs in between 5% and 18% of women.
View the Source
Frequently Asked Questions

When was polycystic ovary syndrome first described?

It was first described in 1935 by Stein and Leventhal.

Polycystic ovary syndrome was first described in 1935, when American gynecologists Irving F. Stein and Michael L. Leventhal published a report linking polycystic ovaries to hirsutism, infertility, and lack of periods. Their names are still attached to the condition's earlier label, Stein-Leventhal syndrome.
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