Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease.
Facts
Mechanism of ActionInhibits the Na-K-Cl cotransporter in the thick ascending limb of the loop of Henle, increasing excretion of sodium, chloride and potassium. 1 Approved UseTreats edema due to heart failure, liver scarring, or kidney disease. 1 First Approved / Isolated Year Significant RiskOrthostatic hypotension, tinnitus and photosensitivity; potentially serious electrolyte abnormalities, low blood pressure and hearing loss. 1 Classification
Approval Status ATC ClassSourced to the subject's own accountC: Cardiovascular System 2 Route of Administration WHO Essential MedicineSourced to the subject's own account Connections
Treats
Source Furosemide (Wikipedia)
Source Furosemide (Wikipedia)
Sources
1. Furosemide (Wikipedia)
Wikimedia FoundationLead section
used to treat edema due to heart failure, liver scarring, or kidney disease
Infobox, drug class
Loop diuretic medication
Mechanism of action section
inhibits the Na-K-Cl cotransporter in the thick ascending limb of the loop of Henle
History section
1964
Adverse effects section
Common side effects include orthostatic hypotension, tinnitus, and photosensitivity
https://en.wikipedia.org/wiki/Furosemide, lead section
ood pressure. It can be taken intravenously or orally. When given intravenously, furosemide typically takes effect within five minutes; when taken orally, it typically metabolizes within an hour.
- Regulatory approval status
View the Source 2. Anatomical Therapeutic Chemical Classification System (Wikipedia)
WikipediaFirst-level anatomical group codes, Code CQuote, First-level anatomical group codes, Code C
Cardiovascular system
3. Wikipedia
Wikipedia contributors, Wikimedia Foundation
4. WHO Model List of Essential Medicines (Wikipedia)
WikipediaWHO Model List of Essential Medicines, Diuretics sectionQuote, WHO Model List of Essential Medicines, Diuretics section
Furosemide
Frequently Asked Questions
What is furosemide used for, and what are its main risks?
A loop diuretic for edema; it can lower potassium and has been associated with hearing damage.
Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. The tendency, as for all loop diuretics, to cause low serum potassium concentration (hypokalemia) has given rise to combination products. Furosemide has been associated with ototoxicity in post-marketing reports and observational studies. This record describes what the sources state and is not medical advice.
When was furosemide approved, and why is it on the anti-doping list?
Approved in 1964; banned in sport because of masking concerns.
Furosemide was patented in 1959 and approved for medical use in 1964. It is on the World Health Organization's List of Essential Medicines. The substance appears on the World Anti-Doping Agency's banned list due to masking concerns.
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