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Drugs and Medicinal Substances

Metoprolol

Cardiovascular System Agents

Metoprolol, sold under the brand names Lopressor and Toprol-XL among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate.

Facts
Drug Class
Beta blocker 1
Mechanism of Action
Selective beta-1 adrenergic receptor antagonist, blocking adrenaline and noradrenaline binding to reduce heart rate, contractility, cardiac output and blood pressure. 1
Approved Use
Treats angina, high blood pressure and conditions involving abnormally fast heart rate. 1
First Approved / Isolated Year
1978 1
Significant Risk
Trouble sleeping, fatigue, feeling faint and abdominal discomfort; large doses may cause serious toxicity. 1
Classification
Approval Status
Approved 1
ATC ClassSourced to the subject's own account
C: Cardiovascular System 2
Route of Administration
Oral 1
Route of Administration
Intravenous 1
Connections

Treats

Hypertension, Conditions
Source Metoprolol (Wikipedia)
Sources
1. Metoprolol (Wikipedia)
Wikimedia Foundation
  • Lead section
    used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate
  • Infobox, drug class
    Beta blocker
  • Mechanism of action section
    Selective beta1-adrenergic receptor antagonist
  • History section
    1978 (FDA approval in the United States)
  • Adverse effects section
    Common side effects include trouble sleeping, feeling tired, feeling faint, and abdominal discomfort
  • Lead section, route-of-administration statement
    It is a beta blocker, specifically a selective competitive β1 receptor blocker, and is taken by mouth or is given intravenously.
  • Lead section, route-of-administration statement (intravenous)
    It is a beta blocker, specifically a selective competitive β1 receptor blocker, and is taken by mouth or is given intravenously.
  • Regulatory approval status
View the Source
2. Anatomical Therapeutic Chemical Classification System (Wikipedia)
WikipediaFirst-level anatomical group codes, Code C
Quote, First-level anatomical group codes, Code C
Cardiovascular system
View the Source
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