Autoimmune polyendocrine syndrome type 1, or APS-1, is a subtype of autoimmune polyendocrine syndrome that causes the dysfunction of multiple endocrine glands through autoimmunity. It is a genetic disorder inherited in an autosomal recessive fashion, caused by a defect in the AIRE gene located on chromosome 21, which normally confers immune tolerance.
Facts
Classification
ICD-10 ChapterIV: Endocrine, Nutritional and Metabolic Diseases 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IVQuote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health OrganizationLead section, transmission-route statement (inferred from disease-category)
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
Main Types section
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
View the Source 3. Autoimmune polyendocrine syndrome type 1 (Wikipedia)
lead sentence 2Quote, lead sentence 2
It causes the dysfunction of multiple endocrine glands due to autoimmunity.
Reader Challenges (0)
No disputes yet. Spotted an error or a better source? Open the first one.
Sign in to dispute this or suggest a correction.