Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. The condition arises from protein misfolding and can be either genetic or acquired. It presents with diverse symptoms depending on the organs affected, commonly including fatigue, swelling of the legs, weight loss, shortness of breath, palpitations, and feeling faint on standing, and in specific types such as AL amyloidosis, patients may develop tongue enlargement and distinctive bruising around the eyes.
Facts
Classification
ICD-10 ChapterIV: Endocrine, Nutritional and Metabolic Diseases 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) First Described Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IVQuote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health OrganizationLead section, transmission-route statement (inferred from disease-category)
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
Main Types section
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
View the Source 3. Amyloidosis (Wikipedia)
Infobox: causes
Genetic or acquired
Article text - era-first-described
Amyloidosis has been described since at least 1639.
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