Haim-Munk syndrome

Haim-Munk syndrome is a skin disease caused by a mutation in the cathepsin C gene, the same gene involved in Papillon-Lefevre syndrome. It is also known as palmoplantar keratoderma with periodontitis and arachnodactyly, acro-osteolysis, and as Cochin Jewish syndrome. One of its features is thick, curved fingernails and toenails. The condition is named for Salim Haim and J. Munk, who first described the disease in 1965. The source lead is short, so this record limits itself to the cause, the alternative names, the nail feature and the naming history it supports.