Microphthalmia-dermal aplasia-sclerocornea syndrome, also known as MLS syndrome, is a rare X-linked dominant, male-lethal disease characterized by unilateral or bilateral microphthalmia together with linear skin defects in affected females, while affected males do not survive to birth. It can be associated with mutations in the HCCS gene.
Facts
Classification
ICD-10 ChapterXVII: Congenital Malformations, Deformations and Chromosomal Abnormalities 2 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) Sources
1. Wikipedia: Microphthalmia-dermal aplasia-sclerocornea syndrome
WikipediaLead: causative agent category
MLS is a rare X-linked dominant male-lethal disease characterized by unilateral or bilateral microphthalmia and linear skin defects in affected females, and in utero lethality for affected males.
Lead section, body-system statement
Microphthalmia-dermal aplasia-sclerocornea syndrome is a condition characterized by linear skin lesions.
View the Source 2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter XVIIQuote, List of chapters, Chapter XVII
Congenital malformations, deformations and chromosomal abnormalities
3. Wikipedia: Non-communicable disease
WikipediaLead section, transmission-route statement (inferred from disease-category)
Genetic disorders are caused by errors in genetic information that produce diseases in the affected people.
Inherited/genetic diseases section
Genetic disorders are caused by errors in genetic information that produce diseases in the affected people.
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