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Condition

IgA Nephropathy

Diseases of the Genitourinary System

IgA nephropathy, also known as Berger's disease, is a disease of the kidney and the immune system, specifically a form of glomerulonephritis, or inflammation of the glomeruli of the kidney. It is the most common glomerulonephritis worldwide, with a global incidence of about 2.5 per 100,000 adults per year, and is characterized by deposition of the IgA antibody in the glomerulus. The disease presents variably, from asymptomatic microscopic blood in the urine to rapid kidney failure, and affects men roughly three times more often than women.

Facts
Classification
Body System
Integumentary System 1
Body System
Cardiovascular System 1
Body System
Lymphatic or Immune System 1
Body System
Digestive System 1
Body System
Urinary System 1
ICD-10 Chapter
XIV: Diseases of the Genitourinary System 2
Communicable or Non-communicable
Non-Communicable 1
First Described
1801 1
Connections

Treated By

Nephrology, Medical Specialties
Sources
1. Wikipedia: IgA nephropathy
Wikipedia
  • History section
    William Heberden the elder first described the disease in 1801 in a 5-year-old child with abdominal pain, hematuria, hematochezia, and purpura of the legs.
  • Lead section, body-system statement
    IgA nephropathy (IgAN), also known as Berger's disease () (and variations), or synpharyngitic glomerulonephritis, is a disease of the kidney (or nephropathy) and the immune system; specifically it is a form of glomerulonephritis or an inflammation of the glomeruli of the kidney.
  • Lead section, body-system statement (lymphatic-immune)
    IgA nephropathy (IgAN), also known as Berger's disease () (and variations), or synpharyngitic glomerulonephritis, is a disease of the kidney (or nephropathy) and the immune system; specifically it is a form of glomerulonephritis or an inflammation of the glomeruli of the kidney.
  • Lead section, body-system statement (integumentary)
    Aggressive Berger's disease (a rarer form of the disease) can attack other major organs, such as the liver, skin and heart.
  • Lead section, body-system statement (digestive)
    Aggressive Berger's disease (a rarer form of the disease) can attack other major organs, such as the liver, skin and heart.
  • Lead section, body-system statement (cardiovascular)
    Aggressive Berger's disease (a rarer form of the disease) can attack other major organs, such as the liver, skin and heart.
View the Source
2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter XIV
Quote, List of chapters, Chapter XIV
Diseases of the genitourinary system
View the Source
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