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Merkel Cell Carcinoma

Neoplasms

Merkel cell carcinoma is an aggressive skin cancer occurring in about three thousand people per year in the United States, also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. Factors involved in its development include the Merkel cell polyomavirus, a weakened immune system, and exposure to ultraviolet radiation, and it usually arises on the head, neck, and extremities as well as the perianal region and eyelid, most often in older white men, with a median age of presentation in the late seventh decade.

Facts
Classification
Body System
Integumentary System 1
Body System
Lymphatic or Immune System 1
ICD-10 Chapter
II: Neoplasms 2
Communicable or Non-communicable
Non-Communicable 3
Transmission Route
Non-Transmissible 3
First Described
1972 1
Sources
1. Merkel-cell carcinoma (Wikipedia)
  • Article text
    Merkel cell carcinoma was first described in 1972 by Cyril Toker.
  • Lead section, body-system statement
    Merkel cell carcinoma (MCC) is an aggressive skin cancer occurring in about three thousand persons per year in the United States.
  • Lead section, body-system statement (lymphatic-immune)
    Factors involved in the development of MCC include the Merkel cell polyomavirus (MCPyV or MCV), a weakened immune system, or exposure to ultraviolet radiation.
View the Source
2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter II
Quote, List of chapters, Chapter II
Neoplasms
View the Source
3. World Health Organization: Noncommunicable diseases (fact sheet)
World Health Organization
  • Lead section, transmission-route statement (inferred from disease-category)
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
  • Main Types section
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
View the Source
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