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Muscle Relaxant Therapy

Pharmacological Therapy

Muscle relaxant therapy uses a drug that affects skeletal muscle function and decreases muscle tone, used to alleviate symptoms such as muscle spasms, pain and hyperreflexia. The term covers two major therapeutic groups: neuromuscular blockers, which act by interfering with transmission at the neuromuscular end plate and have no central nervous system activity, often used during surgical procedures and in intensive care and emergency medicine to cause temporary paralysis; and spasmolytics, or centrally acting muscle relaxants, used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions. Although both groups are sometimes grouped together as muscle relaxants, the term is commonly used to refer to spasmolytics alone.

Facts
Classification
StatusSourced to the subject's own account
Standard of Care 1
Origin YearSourced to the subject's own account
1943 1
Muscle Relaxant Therapy
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FAQs

Who used d-tubocurarine in a Montreal operation in 1942?

Griffith and Johnson did so on 23 January 1942.

On 23 January 1942 in Montreal, Harold Randall Griffith and his resident Enid Johnson used d-tubocurarine, the drug sold as Intocostrin, during an appendicectomy.
Connections

Treats

Source Muscle Relaxant Therapy (Wikipedia)
Source Muscle Relaxant Therapy (Wikipedia)
Source Muscle Relaxant Therapy (Wikipedia)
Sources
1. Muscle Relaxant Therapy (Wikipedia)
Wikipedia
  • History section, neuromuscular blocking drugs paragraph
    By 1943, neuromuscular blocking drugs became established as muscle relaxants in the practice of anesthesia and surgery.
  • Clinical use status
  • Treats: Fibromyalgia, Lead (276141)
    Spasmolytics such as carisoprodol, cyclobenzaprine, metaxalone, and methocarbamol are commonly prescribed for low back pain or neck pain, fibromyalgia, tension headaches and myofascial pain syndrome.
  • Treats: Cerebral Palsy, Lead (279152)
    Muscle relaxants (according to one study) were not advised for orthopedic conditions, but rather for neurological conditions such as spasticity in cerebral palsy and multiple sclerosis.
  • Treats: Multiple Sclerosis, Lead (276134)
    Muscle relaxants (according to one study) were not advised for orthopedic conditions, but rather for neurological conditions such as spasticity in cerebral palsy and multiple sclerosis.
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