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Drugs and Medicinal Substances

Acitretin

Dermatologicals

Acitretin is an oral retinoid medicine that the ChEMBL database records as a small molecule with a retinoid receptor agonist mechanism, approved for psoriasis. ChEMBL gives its first approval as 1996 and its highest development phase as 4, which means it has reached the market, and the World Health Organization classification places it at ATC code D05BB02 in the dermatologicals group. Its adopted name carries the stem -retin, which the United States Adopted Names programme defines as retinol derivatives, and the name was adopted in 1987. ChEMBL flags a boxed warning for the drug, and it records the drug as an oral product, not a parenteral or topical one. This entry records what the sources state and is not medical advice.

Facts
Classification
Approval Status
Approved 1
ATC Class
D: Dermatologicals 2
Route of Administration
Oral 1
First Approved / Isolated Year
1996 1
Connections

Treats

Psoriasis, Conditions
Source ChEMBL, EMBL-EBI: Acitretin approved indications (ChEMBL)
Sources
1. Acitretin (ChEMBL)
  • ChEMBL molecule record, first_approval
    "first_approval": 1996
  • ChEMBL molecule record, max_phase
    "max_phase": "4.0"
  • ChEMBL molecule record, oral flag
    "oral": true
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2. RxNav RxClass, National Library of Medicine: RxClass ATC classes of Acitretin
RxNav RxClass, National Library of MedicineRxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code D05BB (main group D)
Quote, RxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code D05BB (main group D)
"classId": "D05BB", "className": "Retinoids for treatment of psoriasis", "classType": "ATC1-4"
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WHO Collaborating Centre for Drug Statistics Methodology, ATC/DDD Index: the WHO ATC/DDD Index entries named Acitretin
WHO Collaborating Centre for Drug Statistics Methodology, ATC/DDD IndexATC/DDD Index entry; ATC class derived from cited code D05BB02 (main group D)
Quote, ATC/DDD Index entry; ATC class derived from cited code D05BB02 (main group D)
D05BB02 acitretin
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ChEMBL, EMBL-EBI: Acitretin approved indications (ChEMBL)
ChEMBL, EMBL-EBITreats: Psoriasis, drug_indication record, maximum phase 4, MeSH heading Psoriasis
Quote, Treats: Psoriasis, drug_indication record, maximum phase 4, MeSH heading Psoriasis
"max_phase_for_ind": "4.0", "mesh_heading": "Psoriasis", "molecule_chembl_id": "CHEMBL1131"
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