McLeod syndrome is an X-linked recessive genetic disorder that can affect the blood, brain, peripheral nerves, muscle and heart. It results from mutations in the XK gene on the X chromosome, which disrupt production of the Kx protein and, in turn, the Kell blood group antigen system. First described in 1961, McLeod syndrome is a genetic condition rather than a communicable one, so it is not transmitted from person to person.
Facts
Classification
ICD-10 ChapterIII: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) First Described Sources
1. McLeod syndrome (Wikipedia)
Lead paragraph
McLeod syndrome is an X-linked recessive genetic disorder that may affect the blood, brain, peripheral nerves, muscle, and heart.
Infobox, year first described
Year first described: 1961
Lead paragraph, genetic cause
results from mutations in the XK gene on the X chromosome
Lead paragraph, inheritance
X-linked recessive genetic disorder
View the SourceReader Challenges (0)
No disputes yet. Spotted an error or a better source? Open the first one.
Sign in to dispute this or suggest a correction.