Antithrombin III deficiency is a deficiency of antithrombin III, an anticoagulant protein. The deficiency may be inherited or acquired, and is a rare disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism. Hereditary antithrombin deficiency results in a state of increased coagulation that may lead to venous thrombosis, and inheritance is usually autosomal dominant. The disorder was first described by Egeberg in 1965.
Facts
Classification
Body SystemLymphatic or Immune System 1 ICD-10 ChapterIII: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) First Described Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IIIQuote, List of chapters, Chapter III
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
View the Source 2. Wikipedia: Non-communicable disease
WikipediaLead section, transmission-route statement (inferred from disease-category)
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source 3. Antithrombin III deficiency (Wikipedia)
- First described by Egeberg in 1965, article intro
lead paragraph
It is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism, and repetitive intrauterine fetal death (IUFD).
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