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Sjogren Syndrome

Diseases of the Blood and Immune Mechanism

Sjogren syndrome is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly those responsible for producing tears and saliva. Common symptoms include persistent dry mouth and dry eyes, and in a subset of affected people the disease also involves other organ systems, including the lungs, kidneys, and nervous system. It results from the immune system mistakenly attacking the body's own glandular tissue.

Facts
Classification
Body System
Lymphatic or Immune System 1
ICD-10 Chapter
III: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 3
First Described
1892 4
The disease is named after Henrik Sjogren, who described it in 1933; the article credits Jan Mikulicz-Radecki's 1892 case description as the first description of the condition, with the hedge preserved here.
Causative Agent
Causative Agent (category)
Autoimmune 3
Connections

Treated By

Immunosuppressive therapy is used to manage severe systemic manifestations of Sjogren syndrome.

Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter III
Quote, List of chapters, Chapter III
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
View the Source
2. Wikipedia: Non-communicable disease
WikipediaNamed examples section
Quote, Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source
3. Wikipedia: Sjögren's disease
Wikipedia
  • Sjögren's disease (SjD), previously known as Sjögren syndrome or Sjögren's syndrome (SjS, SS), is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the...
  • Lead section, transmission-route statement
    Sjögren's disease (SjD), previously known as Sjögren syndrome or Sjögren's syndrome (SjS, SS), is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the lacrimal and salivary glands.
View the Source
4. Sjogren syndrome (Wikipedia)
Wikipedia: Sjogren Syndrome, History section
Quote, Wikipedia: Sjogren Syndrome, History section
In 1892, he described a 42-year-old man with enlargement of the parotid and lacrimal glands associated with a round-cell infiltrate and acinar atrophy.
View the Source
Wikidata: Sjogren Syndrome
Wikidata Q335555, class allow-list match (w-wdresolver-0926)View the Source
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