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Antithrombin III Deficiency

Diseases of the Blood and Immune Mechanism

Antithrombin III deficiency is a deficiency of antithrombin III, an anticoagulant protein. The deficiency may be inherited or acquired, and is a rare disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism. Hereditary antithrombin deficiency results in a state of increased coagulation that may lead to venous thrombosis, and inheritance is usually autosomal dominant. The disorder was first described by Egeberg in 1965.

Facts
Classification
Body System
Lymphatic or Immune System 1
ICD-10 Chapter
III: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 2
Causative Agent
Causative Agent (category)
Genetic / Hereditary 3
First Described
1965 3
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter III
Quote, List of chapters, Chapter III
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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2. Wikipedia: Non-communicable disease
Wikipedia
  • Lead section, transmission-route statement (inferred from disease-category)
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
  • Named examples section
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
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3. Antithrombin III deficiency (Wikipedia)
  • First described by Egeberg in 1965, article intro
  • lead paragraph
    It is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism, and repetitive intrauterine fetal death (IUFD).
View the Source
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