Milwaukee Shoulder Syndrome

Milwaukee shoulder syndrome is a rare rheumatological condition similar to pseudogout, caused by the deposition of hydroxyapatite or other basic calcium phosphate crystals in and around a joint. It is most often seen in the shoulder but can affect any joint below the head, typically presenting with marked erosion of the humeral head, cartilage, capsule, and bursae on imaging. It occurs most often in women in their fifties or sixties, often with a history of joint trauma, overuse, calcium pyrophosphate dihydrate crystal deposition, neuroarthropathy, dialysis-related arthropathy, or denervation.