Rett syndrome is a rare neurodevelopmental disorder, occurring almost exclusively in females, caused by mutations in the MECP2 gene on the X chromosome. Development typically appears normal for the first six to eighteen months, after which affected children lose purposeful use of their hands, develop repetitive hand-wringing movements, and lose spoken language and motor skills they had gained. Austrian pediatrician Andreas Rett first described the condition in 1966, and the causative MECP2 gene was identified in 1999 by geneticist Huda Zoghbi and colleagues.
Facts
Classification
Body SystemSourced to the subject's own account ICD-10 ChapterV: Mental and Behavioural Disorders 2 Communicable or Non-communicable Transmission RouteSourced to the subject's own account First Described Sources
1. Rett syndrome (Wikipedia)
WikipediaWikipedia infobox, field/specialty parameter
Psychiatry, clinical psychology, pediatrics, neurology
Lead section, transmission-route statement
Rett syndrome (RTT) is a genetic disorder that typically becomes apparent after 6-18 months of age and almost exclusively in girls.
View the Source 2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter VQuote, List of chapters, Chapter V
Mental and behavioural disorders
3. Wikipedia
Wikipedia contributors, Wikimedia Foundationhttps://en.wikipedia.org/wiki/Rett_syndrome, lead sectionQuote, https://en.wikipedia.org/wiki/Rett_syndrome, lead section
Rett syndrome (RTT) is a genetic disorder that typically becomes apparent after 6-18 months of age and almost exclusively in girls. Symptoms include impairments in language and coordination, and repetitive movements. Those affected often have slower growth, di
4. Wikidata: Rett Syndrome
- Wikidata Q917357, class allow-list match (w-wdresolver-0926)
- Wikidata P575 (w-bbfill-medicine3-0926)
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