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Cryoprecipitate Transfusion

Renal and Transfusion Therapy

Cryoprecipitate transfusion delivers cryoprecipitate, a blood product prepared by slowly thawing frozen plasma, collecting the cold-insoluble precipitate that forms, and refreezing it for storage, to a patient in need of the clotting factors it concentrates. Cryoprecipitate carries fibrinogen, Factor VIII, Factor XIII and von Willebrand factor, and although clotting factor concentrates have replaced it in many clinical contexts where they are available, whole cryoprecipitate is still routinely stocked by many hospital blood banks. Compatibility cross-matching is not required before a cryoprecipitate transfusion, though the product should preferably be ABO compatible with the recipient's red blood cells to avoid the rare complications that can follow a large-volume ABO-incompatible transfusion.

Facts
Classification
Status
Standard of Care 1
Origin Year
1964 1
Connections

Treats

Hemophilia, Conditions
Sources
1. Wikipedia: Cryoprecipitate
Wikipedia
  • Section on cryoprecipitate history, sentence naming Judith Graham Pool and 1964
    While the current method for producing cryoprecipitate was developed by Judith Graham Pool from Stanford University in 1964, it was initially approved in 1971 by the U.S. Food and Drug Administration under the name Cryoprecipitated AHF for the Hoxworth Blood Center University of Cincinnati Medical Center.
  • Clinical use status
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