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Drugs and Medicinal Substances

Morphine

Nervous System Agents

Morphine, formerly known as morphium, is an opiate found naturally in opium, a dark brown resin produced by drying the latex of opium poppies. It is mainly used as an analgesic.

Facts
Classification
Approval Status
Approved 1
ATC ClassSourced to the subject's own account
N: Nervous System 2
Route of Administration
Intravenous 1
Route of Administration
Sublingual 1
Route of Administration
Transdermal 1
Route of Administration
Inhalation 1
Route of Administration
Rectal 1
WHO Essential MedicineSourced to the subject's own account
Core List 3
Drug Class
Opioid analgesic 1
Mechanism of Action
Acts as a mu-opioid receptor agonist in the central nervous system to induce analgesia and alter pain perception and emotional response. 1
Approved Use
Used as an analgesic for pain relief. 1
First Approved / Isolated Year
1804 1
Significant Risk
High addiction and abuse potential, respiratory depression, and physical and psychological dependence with withdrawal on dose reduction after long-term use. 1
Connections

Associated With

Long-Form Articles

Sources
1. Morphine (Wikipedia)
Wikimedia Foundation
  • Lead section
    mainly used as an analgesic (pain medication)
  • Infobox, drug class
    Opioid
  • Pharmacology section
    mu-opioid receptor agonist
  • History section
    1804 by German pharmacist Friedrich Serturner
  • Adverse effects section
    high addiction and abuse potential
  • Lead section, route-of-administration statement
    There are multiple methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; intravenously; or via rectal suppository.
  • Lead section, route-of-administration statement (sublingual)
    There are multiple methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; intravenously; or via rectal suppository.
  • Lead section, route-of-administration statement (transdermal)
    There are multiple methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; intravenously; or via rectal suppository.
  • Lead section, route-of-administration statement (inhalation)
    There are multiple methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; intravenously; or via rectal suppository.
  • Lead section, route-of-administration statement (rectal)
    There are multiple methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; intravenously; or via rectal suppository.
  • Regulatory approval status
View the Source
2. Anatomical Therapeutic Chemical Classification System (Wikipedia)
WikipediaFirst-level anatomical group codes, Code N
Quote, First-level anatomical group codes, Code N
Nervous system
View the Source
3. WHO Model List of Essential Medicines (Wikipedia)
WikipediaWHO Model List of Essential Medicines, Opioid analgesics section
Quote, WHO Model List of Essential Medicines, Opioid analgesics section
Morphine
View the Source
Frequently Asked Questions

Why is morphine considered addictive?

It carries high addiction and abuse potential, with dependence and withdrawal after long-term use.

Morphine acts as a mu-opioid receptor agonist in the central nervous system, inducing analgesia and altering pain perception and emotional response. The cited adverse effects section describes high addiction and abuse potential. The entry also records respiratory depression, and physical and psychological dependence with withdrawal on dose reduction after long-term use.

Where does morphine come from?

It is an opiate found naturally in opium, the dried latex of opium poppies.

Morphine is an opiate found naturally in opium, a dark brown resin produced by drying the latex of opium poppies. The cited history section dates its isolation to 1804 by the German pharmacist Friedrich Serturner. It is mainly used as an analgesic.
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