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Multiple organ dysfunction syndrome

Symptoms, Signs and Abnormal Clinical Findings

Multiple organ dysfunction syndrome, or MODS, is altered organ function in an acutely ill patient that requires immediate medical intervention. It develops from infection, injury, poor blood flow or an excessive metabolic demand that triggers an uncontrolled inflammatory response, and sepsis is its most common cause, sometimes progressing to septic shock. The condition typically follows a recognized progression from systemic inflammatory response syndrome with infection, to sepsis, to severe sepsis, and finally to multiple organ dysfunction, though in about a third of cases no single triggering cause can be identified. Case fatality ranges from 30 to 100 percent depending on how many organ systems fail, with the worst outcomes seen in septic shock or major trauma.

Facts
Classification
Body System
Cardiovascular System 1
Body System
Respiratory System 1
Body System
Digestive System 1
Body System
Urinary System 1
ICD-10 Chapter
XVIII: Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified 2
Sources
1. Wikipedia: Multiple organ dysfunction syndrome
Wikipedia
  • Lead section, body-system statement
    Each stage of dysfunction (whether it be the heart, lung, liver, or kidney) has defined parameters, in terms of laboratory values based on blood and other tests, as to what it is (each of these organs' levels of failure is divided into stage I, II, III, IV, and V).
  • Lead section, body-system statement (digestive)
    Each stage of dysfunction (whether it be the heart, lung, liver, or kidney) has defined parameters, in terms of laboratory values based on blood and other tests, as to what it is (each of these organs' levels of failure is divided into stage I, II, III, IV, and V).
  • Lead section, body-system statement (urinary)
    Each stage of dysfunction (whether it be the heart, lung, liver, or kidney) has defined parameters, in terms of laboratory values based on blood and other tests, as to what it is (each of these organs' levels of failure is divided into stage I, II, III, IV, and V).
  • Lead section, body-system statement (cardiovascular)
    Each stage of dysfunction (whether it be the heart, lung, liver, or kidney) has defined parameters, in terms of laboratory values based on blood and other tests, as to what it is (each of these organs' levels of failure is divided into stage I, II, III, IV, and V).
View the Source
2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter XVIII
Quote, List of chapters, Chapter XVIII
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
View the Source
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