BEACOPP is a chemotherapy regimen for treatment of Hodgkin lymphoma, developed by the German Hodgkin Study Group for patients in later stages or with unfavorable early stage risk factors. Patients are typically treated in cycles of twenty one days, with a more intensive fourteen day cycle variant also in use, and a full course usually consists of four to eight cycles, sometimes combined with ABVD. Adoption varies by country: some treat it as standard therapy, while in the United States ABVD is generally used instead out of concern that BEACOPP causes more secondary cancers, although trial results have found no overall difference in treatment related mortality or secondary malignancies between the two regimens.
Facts
Classification
StatusExperimental or Investigational 1 Connections
Treats
Source BEACOPP (Wikipedia)
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia Foundation
Wikidata: BEACOPP
Wikidata Q473727, class allow-list match (w-wdresolver-0926)View the Source BEACOPP (Wikipedia)
Lead section
In the United States, ABVD (or Stanford V) is generally given instead, because of the possibility of BEACOPP inducing more secondary neoplasias (such as leukemias), although the final results from a clinical trial (GHSG HD14) indicate that "there were no overall differences in treatment-related mortality or secondary malignancies" of BEACOPP relative to ABVD.
Treats: Hodgkin Lymphoma, Lead: treats Hodgkin Lymphoma
BEACOPP is a chemotherapy regimen for treatment of Hodgkin lymphoma developed by the German Hodgkin Study Group used for patients in Stages > II or early (IA or IB) with unfavorable risk factors.
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