Hirschsprung's Disease

Hirschsprung's disease is a birth defect in which nerves are missing from parts of the intestine. Its most prominent symptom is constipation, and other symptoms may include vomiting, abdominal pain, diarrhea and slow growth. Most children develop signs and symptoms shortly after birth, though others are diagnosed later in infancy or early childhood, and complications may include enterocolitis, megacolon, bowel obstruction and intestinal perforation.