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Poliomyelitis

Also Known As Polio; Infantile Paralysis
Infectious and Parasitic Diseases

An acute viral infection caused by poliovirus that can invade the nervous system and cause irreversible paralysis within hours, historically striking children in large epidemics through the first half of the twentieth century. The British physician Michael Underwood gave the first clear clinical description in 1789; the poliovirus itself was identified in 1908 by Karl Landsteiner and Erwin Popper. Jonas Salk's inactivated vaccine, introduced in 1955, and Albert Sabin's oral live vaccine, introduced in 1961, made near-global elimination achievable, and the disease is now endemic in only a small number of countries, though not yet certified eradicated.

Facts
Condition Class
infectious, viral 3
Causative Agent
Poliovirus 3
First Described
1789 4
Marks Michael Underwood's first clear clinical description; the poliovirus itself was not identified until 1908, by Karl Landsteiner and Erwin Popper.
Prevalence
Wild poliovirus cases fell from an estimated 350,000 in 1988 to a small number of reported cases in the early 2020s, according to World Health Organization and Global Polio Eradication Initiative data; the disease is not yet certified eradicated. 5
Classification
Body SystemSourced to the subject's own account
Nervous System 1
ICD-10 Chapter
I: Certain Infectious and Parasitic Diseases 2
Communicable or Non-communicable
Communicable 2
Transmission Route
Direct Contact 3
Transmission Route
Fecal-Oral 3
Causative Agent
Causative Agent (category)
Viral 3
Disputed
First Described (Era)
Possible depiction on an Egyptian stele, circa 1400 BCE. 4
An Egyptian stele from around 1400 BCE, depicting a man with a withered, shortened leg leaning on a staff, is widely, though not universally, interpreted by historians as an early depiction of the disease's after-effects; the identification is probable rather than certain.
Poliomyelitis
Filter Results3 entries
FAQs

Which vaccines made near-global elimination of polio achievable?

Salk's inactivated vaccine of 1955 and Sabin's oral vaccine of 1961.

Jonas Salk's inactivated vaccine, introduced in 1955, and Albert Sabin's oral live vaccine, introduced in 1961, made near-global elimination achievable.

Has polio been eradicated?

No, it is endemic in only a small number of countries.

Not yet certified eradicated. The disease is now endemic in only a small number of countries.
Connections

Associated With

Source The Greatest Benefit to Mankind: A Medical History of HumanityRoy Porter

Treated By

Source Hexavalent vaccine (Wikipedia)
Source Polio vaccine (Wikipedia)

Vaccination prevents infection rather than treating active disease; Salk's 1955 inactivated vaccine and Sabin's 1961 oral vaccine are the historically relevant instances recorded on this atlas under the general Vaccination entity.

Source The Greatest Benefit to Mankind: A Medical History of HumanityRoy Porter
Sources
1. Polio (Wikipedia)
WikipediaWikipedia infobox, field/specialty parameter
Quote, Wikipedia infobox, field/specialty parameter
Neurology, infectious disease
View the Source
2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter I
Quote, List of chapters, Chapter I
Certain infectious and parasitic diseases
View the Source
3. Encyclopaedia Britannica
Encyclopaedia Britannica, Inc.
  • Wikidata Q12195 P1060: fecal-oral route
  • Wikidata Q12195 P1060: contact transmission
View the Source
4. The Greatest Benefit to Mankind: A Medical History of Humanity
Roy Porter, W. W. Norton and Company, 1997
5. World Health Organization Fact Sheets
Hexavalent vaccine (Wikipedia)
Treated By: Hexavalent Vaccine, Lead: treats Poliomyelitis
Quote, Treated By: Hexavalent Vaccine, Lead: treats Poliomyelitis
The term usually refers to the children's vaccine that protects against diphtheria, tetanus, pertussis, poliomyelitis, haemophilus B, and hepatitis B, which is used in more than 90 countries around the world including in Europe, Canada, Australia, Jordan, and New Zealand.
View the Source
Polio vaccine (Wikipedia)
Treated By: Polio Vaccine, Lead - treats-condition
Quote, Treated By: Polio Vaccine, Lead - treats-condition
Polio vaccine is a vaccine used to prevent poliomyelitis (polio).
View the Source
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