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Why binimetinib only works as half of a pair

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Binimetinib (Wikipedia)
Development section, NRAS-mutant melanoma trial results paragraph
Quote, Development section, NRAS-mutant melanoma trial results paragraph
In the trial, those receiving binimetinib had a median progression-free survival of 2.8 months versus 1.5 months for those on the standard dacarbazine treatment.
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