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Condition

Amyotrophic Lateral Sclerosis

Diseases of the Nervous System

Amyotrophic lateral sclerosis, also known as motor neuron disease or Lou Gehrig's disease, is a rare and ultimately fatal neurodegenerative disease defined by the progressive loss of the nerve cells that control voluntary muscle movement. It is the most common of the motor neuron diseases and typically begins with gradual muscle stiffness, twitching, and weakness that worsens over time as more motor neurons are lost. The disease eventually impairs the muscles needed for movement, speech, swallowing, and breathing.

Facts
Classification
Body System
Nervous System 1
ICD-10 Chapter
VI: Diseases of the Nervous System 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 2
Causative Agent
Causative Agent (category)
Genetic / Hereditary 3
Causative Agent (category)
Idiopathic / Multifactorial 3
First Described
1824 4
Connections

Associated With

Source Neuroscience (Wikipedia)

Discovered By

Jean-Martin Charcot's 1869 clinical and pathological description first characterized the disease, historically also called Charcot's disease.

Treated By

Physical therapy is standard supportive care to maintain function in amyotrophic lateral sclerosis.

Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter VI
Quote, List of chapters, Chapter VI
Diseases of the nervous system
View the Source
2. Wikipedia: Non-communicable disease
Wikipedia
  • Lead section, transmission-route statement (inferred from disease-category)
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
  • Named examples section
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source
3. ALS (Wikipedia)
infobox causes
Quote, infobox causes
causes: Unknown (90% to 95%) or genetic (5% to 10%)
View the Source
4. Amyotrophic lateral sclerosis (Wikipedia)
Descriptions date back to at least 1824 by Charles Bell, article introView the Source
Wikidata: Amyotrophic Lateral Sclerosis
Wikidata Q206901, class allow-list match (w-wdresolver-0926)View the Source
Neuroscience (Wikipedia)
Associated With: Neuroscience, Clinical neuroscience section
Quote, Associated With: Neuroscience, Clinical neuroscience section
Neurology works with diseases of the central and peripheral nervous systems, such as amyotrophic lateral sclerosis (ALS) and stroke, and their medical treatment.
View the Source
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