Celiac disease is an autoimmune disorder in which ingestion of gluten, a protein found in wheat, barley, and rye, triggers an immune response that damages the lining of the small intestine. This damage impairs the absorption of nutrients and can produce a wide range of digestive and non-digestive symptoms. The disease occurs in genetically predisposed individuals and is a lifelong condition.
Facts
Classification
Body SystemLymphatic or Immune System 1 ICD-10 ChapterIII: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1 Communicable or Non-communicable Transmission Route Partially Attested
First DescribedSamuel Gee gave the first modern description in 1887; earlier descriptions date to antiquity. Condition Class PrevalenceBetween 1 in 50 and 1 in 200 people in most countries 3 Connections
Associated With
Autoimmune small-intestine disorder triggered by gluten; gastroenterology specialty.
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IIIQuote, List of chapters, Chapter III
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
2. Wikipedia: Non-communicable disease
WikipediaNamed examples sectionQuote, Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
3. Wikipedia: Coeliac disease
Lead section, first sentence
Coeliac disease (Commonwealth English) or celiac disease (American English) is a chronic autoimmune disease, mainly affecting the small intestine.
History section, post-1800s
The paediatrician Samuel Gee gave the first modern-day description of the condition in children in a lecture at the Hospital for Sick Children, Great Ormond Street, London, in 1887.
Epidemiology section
In most countries, between 1 in 50 and 1 in 200 people have coeliac disease.
Lead section, transmission-route statement
Coeliac disease (Commonwealth English) or celiac disease (American English) is a chronic autoimmune disease, mainly affecting the small intestine.
View the SourceFrequently Asked Questions
Who gave the first modern description of celiac disease?
Samuel Gee, in a lecture in London in 1887.
The paediatrician Samuel Gee gave the first modern-day description of celiac disease in children, in a lecture at the Hospital for Sick Children on Great Ormond Street in London in 1887.
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