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Cushing's Syndrome

Endocrine, Nutritional and Metabolic Diseases

Cushing's syndrome is a collection of signs and symptoms caused by prolonged exposure to glucocorticoids such as cortisol. Signs and symptoms may include high blood pressure, abdominal obesity with comparatively thin arms and legs, reddish stretch marks, a round red face from facial plethora, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly. Women may have more hair and irregular menstruation or loss of menses, and occasionally there may be changes in mood, headaches, and a chronic feeling of tiredness.

Facts
Classification
Body System
Endocrine System 1
ICD-10 Chapter
IV: Endocrine, Nutritional and Metabolic Diseases 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 2
First Described
1932 3
Connections

Discovered By

Harvey Cushing's 1912 description of the pituitary-driven hormonal syndrome that bears his name is the founding clinical account.

Treated By

Source Hypophysectomy (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IV
Quote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
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2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health Organization
  • Lead section, transmission-route statement (inferred from disease-category)
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
  • Main Types section
    The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
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3. Cushing's Syndrome (Wikipedia)
Wikidata: Cushing's Syndrome
Wikidata Q219102, class allow-list match (w-wdresolver-0926)View the Source
Hypophysectomy (Wikipedia)
Treated By: Hypophysectomy, Lead: treats Cushing's Syndrome
Quote, Treated By: Hypophysectomy, Lead: treats Cushing's Syndrome
Sometimes it is used to treat Cushing's syndrome due to pituitary adenoma or Simmond's disease It is also applied in neurosciences (in experiments with lab animals) to understand the functioning of hypophysis.
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