Cushing's syndrome is a collection of signs and symptoms caused by prolonged exposure to glucocorticoids such as cortisol. Signs and symptoms may include high blood pressure, abdominal obesity with comparatively thin arms and legs, reddish stretch marks, a round red face from facial plethora, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly. Women may have more hair and irregular menstruation or loss of menses, and occasionally there may be changes in mood, headaches, and a chronic feeling of tiredness.
Facts
Classification
ICD-10 ChapterIV: Endocrine, Nutritional and Metabolic Diseases 1 Communicable or Non-communicable Transmission Route First Described Connections
Discovered By
Harvey Cushing's 1912 description of the pituitary-driven hormonal syndrome that bears his name is the founding clinical account.
Treated By
Source Hypophysectomy (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IVQuote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
View the Source 2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health OrganizationLead section, transmission-route statement (inferred from disease-category)
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
Main Types section
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
View the Source 3. Cushing's Syndrome (Wikipedia)
Wikidata: Cushing's Syndrome
Wikidata Q219102, class allow-list match (w-wdresolver-0926)View the Source Hypophysectomy (Wikipedia)
Treated By: Hypophysectomy, Lead: treats Cushing's SyndromeQuote, Treated By: Hypophysectomy, Lead: treats Cushing's Syndrome
Sometimes it is used to treat Cushing's syndrome due to pituitary adenoma or Simmond's disease It is also applied in neurosciences (in experiments with lab animals) to understand the functioning of hypophysis.
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