Dwarfism is a condition marked by unusually small size or short stature, defined in humans as an adult height of 147 centimetres (4 feet 10 inches) or less, with average height among affected people around 120 centimetres. The condition divides into disproportionate dwarfism, where limbs or torso are shortened out of typical proportion, and proportionate dwarfism, where limbs and torso are both unusually small relative to typical stature. Causes include genetic disorders, most commonly achondroplasia which accounts for about 70 percent of cases, and hyposecretion of growth hormone from the pituitary gland. Intelligence is usually normal and most people with dwarfism have a nearly normal life expectancy and retain reproductive capacity, though pregnancy carries added risks depending on the underlying condition. Treatment varies by cause: genetic disorders may be managed with surgery or physical therapy, while growth hormone deficiency can be treated with hormone therapy administered before a child's growth plates fuse.
Facts
Classification
ICD-10 ChapterXVII: Congenital Malformations, Deformations and Chromosomal Abnormalities 2 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) Sources
1. National Library of Medicine MeSH: Dwarfism
National Library of Medicine MeSHMeSH tree number
<http://id.nlm.nih.gov/mesh/D004392> <http://id.nlm.nih.gov/mesh/vocab#treeNumber> <http://id.nlm.nih.gov/mesh/C19.297> .
MeSH tree number C16.320.240
<http://id.nlm.nih.gov/mesh/D004392> <http://id.nlm.nih.gov/mesh/vocab#treeNumber> <http://id.nlm.nih.gov/mesh/C16.320.240> .
View the Source 2. Dwarfism (Wikipedia)
Lead, causes
Achondroplasia is the most common cause of dwarfism, comprising 70% of cases.
Lead, causes [disease-category]
Hyposecretion of growth hormone from pituitary gland (growth hormone deficiency) and genetic disorders.
View the SourceNational Library of Medicine: MeSH Descriptor Data: Dwarfism
National Library of MedicineMeSH tree number C19.297
A genetic or pathological condition that is characterized by short stature and undersize.
MeSH tree number C05.116.099.343
A genetic or pathological condition that is characterized by short stature and undersize.
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