Familial hemiplegic migraine, or FHM, is an autosomal dominant form of hemiplegic migraine. Its attacks typically include weakness of one half of the body that can last hours, days or weeks, and may come with other symptoms such as ataxia, coma and paralysis. Attacks can be provoked by minor head trauma, and in some patients such trauma can lead to delayed cerebral edema, a life-threatening emergency. Three genetic loci are known: FHM1, about half of cases, involves the calcium channel gene CACNA1A and is also linked to cerebellar degeneration; FHM2, under a quarter of cases, involves the sodium-potassium pump gene ATP1A2; and FHM3, a rare subtype, involves the sodium channel gene SCN1A. Sporadic cases without family history appear to share the same causes. The record here describes the condition as medicine understands it and is not medical advice.
Facts
Classification
ICD-10 ChapterVI: Diseases of the Nervous System 1 Communicable or Non-communicable Causative Agent
Causative Agent (category) Sources
1. Familial hemiplegic migraine (Wikipedia)
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FHM1 is also associated with cerebellar degeneration.
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is an autosomal dominant type of hemiplegic migraine
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Familial hemiplegic migraine (FHM) is an autosomal dominant type of hemiplegic migraine that typically includes weakness of half the body which can last for hours, days, or weeks.
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Familial hemiplegic migraine (FHM) is an autosomal dominant type of hemiplegic migraine that typically includes weakness of half the body which can last for hours, days, or weeks.
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