Fanconi syndrome

Fanconi syndrome, or Fanconi's syndrome, is a syndrome of inadequate reabsorption in the proximal renal tubules of the kidney. It can be caused by various underlying congenital or acquired diseases, by toxicity, or by adverse drug reactions, and it results in small molecules of metabolism being passed into the urine instead of being reabsorbed from the tubular fluid. The syndrome affects the proximal convoluted tubule, the first part of the tubule to process fluid after filtration through the glomerulus, and the proximal straight tubule leading to the descending limb of the loop of Henle.