Opsoclonus myoclonus syndrome

Opsoclonus myoclonus syndrome, abbreviated OMS and also called opsoclonus-myoclonus-ataxia or OMA, is a rare neurological disorder whose cause is unknown. It appears to result from an autoimmune process that involves the nervous system. The condition is extremely uncommon, affecting as few as one person in ten million each year. It is seen in about two to three percent of children who have neuroblastoma, and it has also been reported together with celiac disease and with diseases marked by neurologic and autonomic dysfunction. Because the cause is not established, the autoimmune explanation is best read as the leading working account rather than a settled fact.