Protein C deficiency

Protein C deficiency is a rare genetic trait that predisposes a person to thrombotic disease. The Wikipedia lead says it was first described in 1981 and that it belongs to a group of genetic disorders known as thrombophilias. The deficiency is associated with an increased incidence of venous thromboembolism, with a relative risk of 8 to 10, whereas no association with arterial thrombotic disease has been found. The lead is brief and gives no mechanism, symptoms, diagnostic method or treatment, so none is claimed here. This entry records the classification, the date of first description and the stated pattern of clotting risk as the source gives them. It is not medical advice.