Renal agenesis is a medical condition in which one (unilateral) or both (bilateral) fetal kidneys fail to develop, so it is described by whether it affects one side or both. Unilateral and bilateral renal agenesis in humans, mice and zebra fish has been linked to mutations in the gene GREB1L. It has also been associated with mutations in the gene RET in humans and in the gene UPK3A in mice. The source lead therefore presents it as a developmental failure of the kidneys with identified genetic associations across more than one species.
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Causative Agent
Causative Agent (category) Sources
1. Renal agenesis (Wikipedia)
Lead, first sentence
one (unilateral) or both (bilateral) fetal kidneys fail to develop
Lead, second paragraph
has been linked to mutations in the gene GREB1L
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