Peptic ulcer disease refers to damage of the inner part of the stomach's gastric mucosa, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer.
Facts
Classification
ICD-10 ChapterXI: Diseases of the Digestive System 1 Communicable or Non-communicable Condition Classgastroenterologic, surgical 2 First Described Connections
Associated With
Treated By
Source Wikipedia: Billroth II Online Reference Encyclopedia Article
Source ChEMBL, EMBL-EBI: Cimetidine approved indications (ChEMBL)
Source Gastroenterostomy (Wikipedia)
Source ChEMBL, EMBL-EBI: Nizatidine approved indications (ChEMBL)
Source Omeprazole (Wikipedia)
Source Pyloroplasty (Wikipedia)
Vagotomy was historically used to reduce acid secretion in peptic ulcer disease.
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter XIQuote, List of chapters, Chapter XI
Diseases of the digestive system
2. Peptic Ulcer Disease (Wikipedia)
Wikimedia FoundationLead section
Peptic ulcer disease refers to damage of the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus.
- Non-infectious classification
View the Source 3. Peptic ulcer disease (Wikipedia)
First description of a perforated peptic ulcer was in 1670, in Princess Henrietta of England, article introView the Source Omeprazole (Wikipedia)
Wikimedia FoundationTreated By: Omeprazole, Lead sectionQuote, Treated By: Omeprazole, Lead section
peptic ulcer disease
ChEMBL, EMBL-EBI: Cimetidine approved indications (ChEMBL)
ChEMBL, EMBL-EBITreated By: Cimetidine, drug_indication record, maximum phase 4, MeSH heading Peptic UlcerQuote, Treated By: Cimetidine, drug_indication record, maximum phase 4, MeSH heading Peptic Ulcer
"max_phase_for_ind": "4.0", "mesh_heading": "Peptic Ulcer", "molecule_chembl_id": "CHEMBL30"
ChEMBL, EMBL-EBI: Nizatidine approved indications (ChEMBL)
ChEMBL, EMBL-EBITreated By: Nizatidine, drug_indication record, maximum phase 4, MeSH heading Peptic UlcerQuote, Treated By: Nizatidine, drug_indication record, maximum phase 4, MeSH heading Peptic Ulcer
"max_phase_for_ind": "4.0", "mesh_heading": "Peptic Ulcer", "molecule_chembl_id": "CHEMBL3183075"
Wikipedia: Billroth II Online Reference Encyclopedia Article
WikipediaTreated By: Billroth II, Lead: treats Peptic Ulcer DiseaseQuote, Treated By: Billroth II, Lead: treats Peptic Ulcer Disease
The Billroth II is often indicated in refractory peptic ulcer disease and gastric adenocarcinoma.
Gastroenterostomy (Wikipedia)
Treated By: Gastroenterostomy, Lead: treats Peptic Ulcer DiseaseQuote, Treated By: Gastroenterostomy, Lead: treats Peptic Ulcer Disease
The procedure is still being used to treat gastroparesis that is refractory to other treatments, but it is now rarely used to treat peptic ulcers because most cases thereof are bacterial in nature (due to Helicobacter pylori) and there are many new drugs available to treat the gastric reflux often experienced with peptic ulcer disease.
Pyloroplasty (Wikipedia)
Treated By: Pyloroplasty, ApplicationsQuote, Treated By: Pyloroplasty, Applications
It also can be performed on patients at high risk for gastric or peptic ulcer disease (PUD).
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