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Tuberculosis

Also Known As Consumption; TB; Phthisis
Infectious and Parasitic Diseases

A chronic infectious disease caused by the bacterium Mycobacterium tuberculosis, most often affecting the lungs, historically called consumption for the wasting it produced. It was among the leading causes of death in nineteenth-century Europe and, per the World Health Organization, remains one of the world's leading infectious killers. Robert Koch identified the causative bacillus in 1882, a discovery that helped establish germ theory; effective antibiotic treatment did not arrive until streptomycin's introduction in the 1940s.

Facts
Condition Class
infectious, bacterial, chronic 3
Causative Agent
Mycobacterium tuberculosis 3
First Described
1882 4
Marks Robert Koch's identification of the tuberculosis bacillus, not the first recognition of the disease itself, which is far older.
First Described (Era)
Skeletal evidence of tuberculosis has been found in human remains thousands of years old, and the Greek physician Hippocrates described the disease, under the name phthisis, circa 400 BCE. 4
Prevalence
An estimated 10.6 million people fell ill with tuberculosis in 2022, and it remained one of the world's leading infectious causes of death, according to World Health Organization data. 5
Classification
Body SystemSourced to the subject's own account
Respiratory System 1
ICD-10 Chapter
I: Certain Infectious and Parasitic Diseases 2
Communicable or Non-communicable
Communicable 2
Transmission RouteSourced to the subject's own account
Airborne 1
Causative Agent
Causative Agent (category)
Bacterial 3
FAQs

Who identified the bacterium that causes tuberculosis?

Robert Koch, in 1882.

Robert Koch identified the causative bacillus in 1882, a discovery that helped establish germ theory.

Why was tuberculosis once called consumption?

Because of the wasting it produced.

It was historically called consumption for the wasting that the disease produced.
Connections

Associated With

Germ Theory of Disease, Discoveries

Koch's 1882 identification of the tuberculosis bacillus is part of the same evidentiary program, Koch's postulates, that established germ theory.

Source The Greatest Benefit to Mankind: A Medical History of HumanityRoy Porter
Source Infectious Disease Subspecialties Career Information
X-rays, Discoveries

Chest radiography became central to tuberculosis diagnosis and to twentieth-century mass screening campaigns.

Source The Greatest Benefit to Mankind: A Medical History of HumanityRoy Porter

Long-Form Articles

Treated By

Effective treatment requires a multi-drug antibiotic regimen (streptomycin from the 1940s, later isoniazid and rifampin) sustained for months; a single antibiotic alone permits resistant strains to emerge.

Source The Greatest Benefit to Mankind: A Medical History of HumanityRoy Porter
Source BCG vaccine (Wikipedia)
Colloidal Silver, Treatments
Source Medical uses of silver (Wikipedia)
Source Contact tracing (Wikipedia)

Directly observed treatment, short course, known as DOTS, is the World Health Organization strategy for treating tuberculosis.

Gerson Therapy, Treatments
Source Max Gerson (Wikipedia)
Source Management of tuberculosis (Wikipedia)
Source Ozone therapy - Wikipedia
Source Streptomycin (Wikipedia)
Sources
1. Tuberculosis (Wikipedia)
Wikipedia
  • Wikipedia infobox, field/specialty parameter
    Infectious disease, pulmonology
  • Lead section, transmission-route statement
    Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze.
View the Source
2. Wikipedia: ICD-10
WikipediaList of chapters, Chapter I
Quote, List of chapters, Chapter I
Certain infectious and parasitic diseases
View the Source
3. Encyclopaedia Britannica
Encyclopaedia Britannica, Inc.View the Source
4. The Greatest Benefit to Mankind: A Medical History of Humanity
Roy Porter, W. W. Norton and Company, 1997
5. World Health Organization Fact Sheets
Infectious Disease Subspecialties Career Information
American College of PhysiciansAssociated With: Infectious DiseaseView the Source
Streptomycin (Wikipedia)
Wikimedia FoundationTreated By: Streptomycin, Lead section
Quote, Treated By: Streptomycin, Lead section
used to treat a number of bacterial infections, including tuberculosis
View the Source
Management of tuberculosis (Wikipedia)
Treated By: Management of Tuberculosis, Lead: treats Tuberculosis
Quote, Treated By: Management of Tuberculosis, Lead: treats Tuberculosis
A patient is expected to be free from all living TB bacteria after six months of therapy in Pulmonary TB or 8-10 months in Miliary TB. Latent tuberculosis or latent tuberculosis infection (LTBI) is treated with three to nine months of isoniazid alone.
View the Source
BCG vaccine (Wikipedia)
Treated By: BCG Vaccine, Lead - treats-condition
Quote, Treated By: BCG Vaccine, Lead - treats-condition
The Bacillus Calmette-Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB).
View the Source
Ozone therapy - Wikipedia
Treated By: Ozone Therapy, Article text, use for Tuberculosis
Quote, Treated By: Ozone Therapy, Article text, use for Tuberculosis
In 1892 The Lancet published an article describing the administration of ozone for treatment of tuberculosis.
View the Source
Contact tracing (Wikipedia)
Treated By: Contact Tracing, Outbreaks
Quote, Treated By: Contact Tracing, Outbreaks
Diseases for which contact tracing is commonly performed include tuberculosis, vaccine-preventable infections like measles, sexually transmitted infections (including HIV), blood-borne infections, Ebola, bacterial infections, and novel virus infections (e.g., SARS-CoV, H1N1, and SARS-CoV-2).
View the Source
Max Gerson (Wikipedia)
Treated By: Gerson Therapy, Medical career
Quote, Treated By: Gerson Therapy, Medical career
By 1927, he was specializing in the treatment of tuberculosis, developing the Gerson-Sauerbruch-Hermannsdorfer diet, claiming it was a major advance in the treatment of tuberculosis.
View the Source
Medical uses of silver (Wikipedia)
Treated By: Colloidal Silver, Alternative medicine
Quote, Treated By: Colloidal Silver, Alternative medicine
Since about 1990, there has been a resurgence of the promotion of colloidal silver as a dietary supplement (used internally), marketed with claims of its being an essential mineral supplement, or that it can prevent or treat numerous diseases, such as cancer, diabetes, arthritis, HIV/AIDS, herpes, and tuberculosis.
View the Source
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