Discovery

Discovery of the Graafian follicle

Molecular, Genetic and Metabolic Discovery

The Graafian follicle is the mature ovarian follicle, named after the Dutch physician Regnier de Graaf, who described its development in his treatise on the female organs of generation published at Leiden in 1672. De Graaf himself pointed out that he was not the first to describe the follicles, and Fallopius and others had noticed them earlier without recognising their reproductive significance. From rabbit experiments he concluded that the follicle contained the egg, although he took the whole follicle for the egg, and the mammalian egg was not found until Karl Ernst von Baer in 1827. Jan Swammerdam accused him of claiming discoveries about the ovary that Swammerdam and Johannes van Horne had made earlier.

Facts
Discovery Year
1672 1
Dispute Status
Priority Disputed 1
Classification
Type/Classification
Basic Science Knowledge 1
Connections

Discovered By

Source Regnier de Graaf (Wikipedia)

Discoveries

Source Regnier de Graaf (Wikipedia)
Sources
1. Encyclopedia.com: Graaf, Regnier De
Encyclopedia.com
  • Bibliography, 1672 treatise
    tractatus novus... (Leiden, 1672)
  • Entry text, Graafian follicle
    his crucial role in the accurate and concrete description of the anatomy and physiology of the female mammalian reproductive organs
  • Entry text, Swammerdam
    violent hostility as a result of priority disputes
View the Source
Regnier de Graaf (Wikipedia)
  • Discovered By: Regnier de Graaf, Legacy, Graafian follicles
    His eponymous legacy are the Graafian follicles
  • Discoveries: Regnier de Graaf, Legacy, Graafian follicles
    His eponymous legacy are the Graafian follicles
View the Source
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