Systemic lupus erythematosus is a chronic autoimmune disease in which the immune system attacks healthy tissue throughout the body, potentially affecting the skin, joints, kidneys, blood cells, and other organs. Its course is marked by periods of flares and remission, and its symptoms and severity vary widely between individuals. The precise cause is not fully understood, though genetic, hormonal, and environmental factors are believed to contribute.
Facts
Classification
Body SystemLymphatic or Immune System 1 ICD-10 ChapterIII: Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism 1 Communicable or Non-communicable Transmission Route Condition Class Prevalence20 to 70 per 100,000, varying by country 4 Causative Agent
Causative Agent (category) Connections
Treated By
Source CART4-34 therapy (Wikipedia)
Source Immunosuppression (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IIIQuote, List of chapters, Chapter III
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
2. Wikipedia: Non-communicable disease
WikipediaNamed examples sectionQuote, Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
3. Wikipedia: Lupus
Wikipedia- Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
Lead section, transmission-route statement
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
View the Source 4. Wikipedia: Systemic lupus erythematosus
Lead section, first sentence
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
Epidemiology section
Rate of SLE varies between countries from 20 to 70 per 100,000. Women of childbearing age are affected about nine times more often than men.
View the SourceWikidata: Systemic Lupus Erythematosus
Immunosuppression (Wikipedia)
Treated By: Immunosuppression, Lead: treats Systemic Lupus ErythematosusQuote, Treated By: Immunosuppression, Lead: treats Systemic Lupus Erythematosus
Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease.
CART4-34 therapy (Wikipedia)
Treated By: CART4-34 therapy, Lead: treats Systemic Lupus ErythematosusQuote, Treated By: CART4-34 therapy, Lead: treats Systemic Lupus Erythematosus
It attempts to treat certain B-cell lymphomas and autoimmune diseases such as systemic lupus erythematosus (SLE).
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