Ethotoin is a small-molecule anticonvulsant with the molecular formula C11H12N2O2 and a molecular weight of about 204.23, recorded in the ChEMBL database as an approved drug whose first approval year is 1957. Its nonproprietary name carries the stem -toin, which ChEMBL defines as the antiepileptics that are hydantoin derivatives. The WHO Anatomical Therapeutic Chemical index files it as N03AB01 among the hydantoin derivatives in the antiepileptics group, which comprises preparations used in the treatment of epilepsy and related conditions, and assigns a defined daily dose of 2.5 g for oral use. ChEMBL lists its approved indications as epilepsy and seizures. This entry records classification and approval facts only and is not medical advice.
Facts
Classification
Approval Status Route of Administration First Approved / Isolated Year Connections
Treats
Source ChEMBL, EMBL-EBI: Ethotoin approved indications (ChEMBL)
Sources
1. Ethotoin (ChEMBL molecule record)
ChEMBL molecule record, first_approval
"first_approval": 1957
ChEMBL molecule record, max_phase 4
"max_phase": "4.0"
ChEMBL molecule record, oral flag
"oral": true
View the Source2. RxNav RxClass, National Library of Medicine: RxClass ATC classes of Ethotoin
RxNav RxClass, National Library of MedicineRxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code N03AB (main group N)Quote, RxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code N03AB (main group N)
"classId": "N03AB", "className": "Hydantoin derivatives", "classType": "ATC1-4"
ChEMBL, EMBL-EBI: ChEMBL molecule record CHEMBL1095 (Ethotoin)
ChEMBL, EMBL-EBIatc_classifications of the molecule record; ATC class derived from cited code N03AB01 (main group N)Quote, atc_classifications of the molecule record; ATC class derived from cited code N03AB01 (main group N)
"atc_classifications": [ "N03AB01" ], "molecule_chembl_id": "CHEMBL1095", "pref_name": "ETHOTOIN"
ChEMBL, EMBL-EBI: Ethotoin approved indications (ChEMBL)
ChEMBL, EMBL-EBITreats: Epilepsy, drug_indication record, maximum phase 4, MeSH heading EpilepsyQuote, Treats: Epilepsy, drug_indication record, maximum phase 4, MeSH heading Epilepsy
"max_phase_for_ind": "4.0", "mesh_heading": "Epilepsy", "molecule_chembl_id": "CHEMBL1095"
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