Isotretinoin is a small-molecule drug that the ChEMBL database records as molecule CHEMBL547. ChEMBL gives 1982 as the year of its first approval and a maximum clinical phase of 4, which means it has reached approved use, and the record shows it has not been withdrawn. The same record flags the drug as an oral medicine and not as a parenteral or topical product. ChEMBL names acne vulgaris as its approved indication, which places it among the skin medicines. Under the WHO Anatomical Therapeutic Chemical system it is classed with the dermatologicals. This entry records classification and approval facts only and is not medical advice.
Facts
Classification
Approval Status Route of Administration First Approved / Isolated Year Connections
Treats
Source ChEMBL, EMBL-EBI: Isotretinoin approved indications (ChEMBL)
Sources
1. Isotretinoin (ChEMBL)
ChEMBL molecule CHEMBL547, first_approval
"first_approval": 1982
ChEMBL molecule CHEMBL547, max_phase
"max_phase": "4.0"
ChEMBL molecule CHEMBL547, oral flag
"oral": true
View the Source2. RxNav RxClass, National Library of Medicine: RxClass ATC classes of Isotretinoin
RxNav RxClass, National Library of MedicineRxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code D10AD (main group D)Quote, RxClass ATC class of the drug (levels 1 to 4); ATC class derived from cited code D10AD (main group D)
"classId": "D10AD", "className": "Retinoids for topical use in acne", "classType": "ATC1-4"
ChEMBL, EMBL-EBI: Isotretinoin approved indications (ChEMBL)
ChEMBL, EMBL-EBITreats: Acne, drug_indication record, maximum phase 4, MeSH heading Acne VulgarisQuote, Treats: Acne, drug_indication record, maximum phase 4, MeSH heading Acne Vulgaris
"max_phase_for_ind": "4.0", "mesh_heading": "Acne Vulgaris", "molecule_chembl_id": "CHEMBL547"
Reader Challenges (0)
No disputes yet. Spotted an error or a better source? Open the first one.
Sign in to dispute this or suggest a correction.