Hematopoietic stem cell transplantation, usually abbreviated HSCT, is the transplantation of multipotent hematopoietic stem cells, usually taken from bone marrow, peripheral blood or umbilical cord blood, so that they replicate inside a patient and produce new normal blood cells. It may be autologous, using the patient's own stem cells, syngeneic, using cells from an identical twin, or allogeneic, using cells from a donor, and before an allogeneic or autologous transplant the recipient's immune system is usually suppressed with radiation or chemotherapy. HSCT is most often performed for cancers of the blood or bone marrow such as multiple myeloma, leukemia and some lymphomas, as well as for immune deficiencies, and as survival outcomes have improved its use has expanded to autoimmune diseases and inherited conditions such as osteopetrosis and mucopolysaccharidosis.
Facts
Connections
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia FoundationWikipedia, Hematopoietic stem cell transplantation, History section, first paragraph
In 1939, a woman with aplastic anaemia received the first human bone marrow transfusion.
https://en.wikipedia.org/wiki/Hematopoietic_stem_cell_transplantation, lead section
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.
View the Source Reader Challenges (0)
No disputes yet. Spotted an error or a better source? Open the first one.
Sign in to dispute this or suggest a correction.
View At A Past Year
Choose a year to see this entry's facts and connections as the atlas records them at that moment: what it held then, what it held instead, and what it had not yet adopted. Choose Present for the current record.