Immunoglobulin therapy is the use of a mixture of antibodies drawn from human plasma, called normal human immunoglobulin, to treat a range of health conditions, given by injection into a vein, a muscle or under the skin, with effects lasting several weeks. The therapy dates to the 1930s, initially given by intramuscular injection in the 1950s before an intravenous formulation was approved by the FDA in 1981 and a subcutaneous option became available in the 1990s. It is used to treat primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, Guillain-Barre syndrome and some cases of HIV/AIDS and measles, and is included on the World Health Organization's List of Essential Medicines.
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1. Wikipedia
Wikipedia contributors, Wikimedia Foundationhttps://en.wikipedia.org/wiki/Immunoglobulin_therapy, lead sectionQuote, https://en.wikipedia.org/wiki/Immunoglobulin_therapy, lead section
Immunoglobulin therapy is the use of a mixture of antibodies to treat several health conditions.
2. Wikipedia: Immunoglobulin Therapy
Wikimedia FoundationRoutes of administration, 1950s intramuscular subsectionQuote, Routes of administration, 1950s intramuscular subsection
After immunoglobulin therapy's discovery in 1952, weekly intramuscular injections of immunoglobulin (IMIg) were the norm until intravenous formulations (IVIg) began to be introduced in the 1980s.
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