Chemoprophylaxis, also called chemoprevention, is the administration of a medication to prevent disease or infection before it occurs, rather than to treat an existing illness. Antibiotics are a common example, given to immunocompromised patients to guard against bacterial infection or to otherwise healthy people during a disease outbreak to limit its spread, and the approach is also used to prevent recurrent infections, such as repeated urinary tract infections, and to keep a localized infection from spreading to other organ systems. Its use is limited chiefly by two factors: the medication's side effects may outweigh the preventive benefit, and the cost of treating a whole population can be impractical when the underlying disease is rare or the drug itself is expensive.
Facts
Disputed
Origin YearMarks the earliest documented case of drug-based malaria chemoprophylaxis found by the cited historical review: cinchona bark used to suppress malaria in soldiers during the Siege of Belgrade in 1717. Not a claim about when the term chemoprophylaxis itself was coined, only the earliest attested practice of this kind. Connections
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia Foundationhttps://en.wikipedia.org/wiki/Chemoprophylaxis, lead sectionQuote, https://en.wikipedia.org/wiki/Chemoprophylaxis, lead section
Chemoprevention or chemoprophylaxis refers to the administration of a medication for the purpose of preventing disease or infection.
View the Source 2. Historical Review: Problematic Malaria Prophylaxis with Quinine
G. Dennis Shanks, The American Journal of Tropical Medicine and Hygiene, 2016Chemoprophylaxis sectionQuote, Chemoprophylaxis section
As early as the Siege of Belgrade in 1717, cinchona bark was being used to suppress malaria in soldiers.
View the Source Frequently Asked Questions
How long has medication been used to prevent malaria rather than treat it?
Cinchona bark was used to suppress malaria in soldiers as early as 1717.
Chemoprophylaxis means giving a medication to prevent disease before it occurs rather than to treat an existing illness. As early as the Siege of Belgrade in 1717, cinchona bark was being used to suppress malaria in soldiers, and malaria remains the disease the atlas links to this approach.
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