Hemoperfusion is a method of filtering the blood extracorporeally, outside the body, to remove a toxin: as in hemodialysis and hemofiltration, blood travels from the patient into a machine, is filtered, and returns to the patient, typically through venovenous access. In hemoperfusion the blood perfuses a filter of artificial cells filled with activated carbon or another microporous material, so that small toxin molecules cross into the material and are trapped there while blood cells brush past intact. First introduced in the 1940s and refined through the 1950s to 1970s, it entered clinical use for poisoning in the 1970s and 1980s and today treats drug overdose and specific intoxications such as valproic acid, theophylline and meprobamate, though it remains only infrequently used.
Facts
Partially Attested
Origin YearSourced to the subject's own accountWikipedia gives only the decade: first introduced in the 1940s, refined through the 1950s-1970s, and introduced clinically for poisoning treatment in the 1970s-1980s; no single year is stated in the source text. Connections
Associated With
Hemoperfusion is a blood detoxification procedure within hematology.
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia Foundationhttps://en.wikipedia.org/wiki/Hemoperfusion, lead sectionQuote, https://en.wikipedia.org/wiki/Hemoperfusion, lead section
Hemoperfusion or hæmoperfusion is a method of filtering the blood extracorporeally to remove a toxin.
2. Hemoperfusion (Wikipedia)
WikipediaLead section, introduction and clinical adoption paragraphQuote, Lead section, introduction and clinical adoption paragraph
First introduced in the 1940s, hemoperfusion was refined during the 1950s through 1970s, and then introduced clinically for the treatment of poisoning in the 1970s and 1980s.
Frequently Asked Questions
What does hemoperfusion remove from the blood that a dialysis membrane cannot
It filters blood through a bed of activated carbon or another adsorbent material rather than a dialysis membrane, trapping toxin molecules a membrane alone cannot remove.
Hemoperfusion is a method of filtering the blood extracorporeally, outside the body, to remove a toxin. As in hemodialysis and hemofiltration, blood travels from the patient into a machine, is filtered, and returns to the patient, typically through venovenous access, but the blood perfuses a filter of artificial cells filled with activated carbon or another microporous material, so small toxin molecules cross into the material and are trapped there while blood cells brush past intact. First introduced in the 1940s, hemoperfusion was refined through the 1950s to 1970s and then introduced clinically for the treatment of poisoning in the 1970s and 1980s.
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