Epilepsy is a group of neurological disorders characterized by a tendency for recurrent, unprovoked seizures. A seizure is a sudden burst of abnormal electrical activity in the brain that can cause a variety of symptoms, ranging from brief lapses of awareness or muscle jerks to prolonged convulsions.
Facts
Classification
ICD-10 ChapterVI: Diseases of the Nervous System 1 Communicable or Non-communicable Transmission Route Condition Class First Described Causative Agent
Causative Agent (category)Idiopathic / Multifactorial 3 Epilepsy
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Associated With
Source Neuroscience (Wikipedia)
Treated By
Source Amygdalohippocampectomy (Wikipedia)
Source Anterior temporal lobectomy (Wikipedia)
Source Commissurotomy (Wikipedia)
Corpus callosotomy is used for severe, drug-resistant epilepsy.
Source Epilepsy surgery (Wikipedia)
Source ChEMBL, EMBL-EBI: Ethotoin approved indications (ChEMBL)
Source Hagiotherapy (Wikipedia)
Hemispherectomy is used for severe epilepsy confined to one cerebral hemisphere.
Source Medical cannibalism (Wikipedia)
Source Transcranial focused ultrasound (Wikipedia)
Source Transcranial pulsed ultrasound (Wikipedia)
Source Wikipedia: Trepanning
Source Wikipedia: Trepanning
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter VIQuote, List of chapters, Chapter VI
Diseases of the nervous system
2. Wikipedia: Non-communicable disease
WikipediaLead section, transmission-route statement (inferred from disease-category)
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source 3. Epilepsy (Wikipedia)
Wikimedia FoundationLead section
Epilepsy is a group of neurological disorders characterized by a tendency for recurrent, unprovoked seizures.
- intro para 2
History section
The world's oldest description of an epileptic seizure comes from a text in Akkadian (a language used in ancient Mesopotamia) and was written around 2000 BC.
View the Source Neuroscience (Wikipedia)
Associated With: Neuroscience, History sectionQuote, Associated With: Neuroscience, History section
In the process of treating epilepsy, Wilder Penfield produced maps of the location of various functions (motor, sensory, memory, vision) in the brain.
Amygdalohippocampectomy (Wikipedia)
ChEMBL, EMBL-EBI: Ethotoin approved indications (ChEMBL)
ChEMBL, EMBL-EBITreated By: Ethotoin, drug_indication record, maximum phase 4, MeSH heading EpilepsyQuote, Treated By: Ethotoin, drug_indication record, maximum phase 4, MeSH heading Epilepsy
"max_phase_for_ind": "4.0", "mesh_heading": "Epilepsy", "molecule_chembl_id": "CHEMBL1095"
Wikipedia: Trepanning
WikipediaTreated By: Trepanation, Lead: treats Epilepsy
The primary theories for the practice of trepanation in ancient times include spiritual purposes and treatment for epilepsy, head wounds, mental disorders, and headaches, although the latter may be just an unfounded myth.
Treated By: Trepanning, Lead: treats Epilepsy
The primary theories for the practice of trepanation in ancient times include spiritual purposes and treatment for epilepsy, head wounds, mental disorders, and headaches, although the latter may be just an unfounded myth.
View the Source Hagiotherapy (Wikipedia)
Treated By: Hagiotherapy, Lead: treats EpilepsyQuote, Treated By: Hagiotherapy, Lead: treats Epilepsy
It was used to treat epilepsy during the Middle Ages with Saint Valentine particularly associated with the treatment as an 'epilepsy specialist'.
Epilepsy surgery (Wikipedia)
Treated By: Epilepsy Surgery, Lead: treats EpilepsyQuote, Treated By: Epilepsy Surgery, Lead: treats Epilepsy
Such patients are potential candidates for surgical epilepsy treatment.
Anterior temporal lobectomy (Wikipedia)
Treated By: Anterior Temporal Lobectomy, Lead: treats EpilepsyQuote, Treated By: Anterior Temporal Lobectomy, Lead: treats Epilepsy
It is a treatment option for temporal lobe epilepsy for those in whom anticonvulsant medications do not control epileptic seizures, and who have frequent seizures, and who additionally qualify based on a WADA test to localize the dominant hemisphere for language module.
Commissurotomy (Wikipedia)
Treated By: Commissurotomy, Article text, use for EpilepsyQuote, Treated By: Commissurotomy, Article text, use for Epilepsy
In neurosurgery, as a treatment for severe epilepsy, the corpus callosum, or the area of the brain that connects the two hemispheres, would be completely bisected.
Transcranial pulsed ultrasound (Wikipedia)
Treated By: Transcranial Pulsed Ultrasound, Article text, use forQuote, Treated By: Transcranial Pulsed Ultrasound, Article text, use for
Scientists continue to test a variety of mammals such as humans, monkeys and mice on positively affecting the treatment of epilepsy, Parkinson's disease, chronic pain, coma, dystonia, psychoses and depression by applying safe, low-intensity, TPU.
Transcranial focused ultrasound (Wikipedia)
Treated By: Transcranial focused ultrasound, Article text, use forQuote, Treated By: Transcranial focused ultrasound, Article text, use for
Applications of tFUS neuromodulation in clinical practice may include treatment of essential tremor, treatment-resistant major depressive disorder (MDD), post-stroke chronic pain, epilepsy, obsessive-compulsive disorder (OCD), and anxiety.
Medical cannibalism (Wikipedia)
Treated By: Medical Cannibalism, EuropeQuote, Treated By: Medical Cannibalism, Europe
In the early 19th century, Englishmen still treated epilepsy by mixing skull with molasses.
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