Type 1 diabetes, also called type 1 diabetes mellitus, is an autoimmune disease that occurs when the body's immune system destroys the beta cells in the pancreas that produce the hormone insulin. Insulin is used by the body to store and convert blood sugar into energy, so type 1 diabetes results in high blood sugar levels prior to treatment due to the lack of insulin. Common symptoms include frequent urination, increased thirst, increased hunger, and weight loss, and additional symptoms may include blurry vision, tiredness, and slow wound healing. While some cases take longer to develop, symptoms usually appear within weeks to a few months.
Facts
Classification
ICD-10 ChapterIV: Endocrine, Nutritional and Metabolic Diseases 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) Type 1 Diabetes
Filter Results6 entries
Connections
Treated By
Source Adoptive cell transfer (Wikipedia)
Source Automated insulin delivery system (Wikipedia)
Insulin therapy is the essential standard treatment for type 1 diabetes.
Source Islet cell transplantation (Wikipedia)
Source Pancreas Transplantation (Wikipedia)
Source Tolerogenic therapy (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter IVQuote, List of chapters, Chapter IV
Endocrine, nutritional and metabolic diseases
2. World Health Organization: Noncommunicable diseases (fact sheet)
World Health OrganizationMain Types sectionQuote, Main Types section
The main types of NCDs are cardiovascular diseases (such as heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes.
3. Wikipedia: Type 1 diabetes
WikipediaArticle text
Type 1 diabetes (T1D), or type 1 diabetes mellitus, is an autoimmune disease that occurs when the body's immune system destroys beta cells in the pancreas that produce the hormone insulin.
Lead section, transmission-route statement
Type 1 diabetes (T1D), or type 1 diabetes mellitus, is an autoimmune disease that occurs when the body's immune system destroys beta cells in the pancreas that produce the hormone insulin.
View the Source Islet cell transplantation (Wikipedia)
Treated By: Islet Transplantation, Lead: treats Type 1 DiabetesQuote, Treated By: Islet Transplantation, Lead: treats Type 1 Diabetes
It is a treatment for type 1 diabetes.
Tolerogenic therapy (Wikipedia)
Treated By: Tolerogenic Therapy, Lead: treats Type 1 DiabetesQuote, Treated By: Tolerogenic Therapy, Lead: treats Type 1 Diabetes
Research using animal models in transplantation and autoimmune diseases has led to early-phase human trials of tolerogenic therapy for autoimmune conditions like Type 1 Diabetes.
Pancreas Transplantation (Wikipedia)
WikipediaTreated By: Pancreas Transplantation, Article text, use for Type 1 DiabetesQuote, Treated By: Pancreas Transplantation, Article text, use for Type 1 Diabetes
Sutherland, whole pancreas transplantation began as a part of multi-organ transplants, in the mid-to-late 1960s, at the University of Minnesota:The first attempt to cure type 1 diabetes by pancreas transplantation was done at the University of Minnesota, in Minneapolis, on December 17, 1966… [This] opened the door to a period, between the mid 70's to mid 80's where only segmental pancreatic grafts were used...
Adoptive cell transfer (Wikipedia)
Treated By: Adoptive Cell Transfer, Autoimmune diseaseQuote, Treated By: Adoptive Cell Transfer, Autoimmune disease
The transfer of regulatory T cells has been used to treat Type 1 diabetes and others.
Automated insulin delivery system (Wikipedia)
Treated By: Automated Insulin Delivery System, PhysiologicalQuote, Treated By: Automated Insulin Delivery System, Physiological
In November 2018, it was announced that Defymed would partner with the Israel-based Kadimastem, a bio-pharmaceutical company developing stem-cell based regenerative therapies, to receive a two-year grant worth approximately $1.47 million for the development of a bio-artificial pancreas that would treat type 1 diabetes.
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