Medicine Atlas

How Healing Is Practiced
Treatments

Insulin Therapy

Also Known As Insulin Replacement Therapy

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Insulin therapy treats diabetes mellitus by replacing the hormone insulin, which the body can no longer produce or use effectively. A team at the University of Toronto, physiologist John Macleod, surgeon Frederick Banting, medical student Charles Best and biochemist James Collip, isolated and purified insulin from animal pancreases over the course of 1921 and early 1922. Banting and Macleod alone received the 1923 Nobel Prize; Banting judged the choice of Macleod over Best unjust and split his own prize money with Best, and Macleod in turn split his with Collip, an implicit acknowledgment by both laureates that the official credit was too narrow. This atlas describes the history of the treatment and is not medical advice.

Facts
Disputed
Origin Year
1921 1
Insulin was isolated in 1921, but Best and Collip's biochemical extraction method, developed within days of each other in early 1922, was what made a purified, clinically usable insulin possible; historians still debate how credit for the discovery should be divided among the four researchers, and 1922 is used by some accounts as the true origin year of insulin as a usable treatment.
Cross-Tradition Connections

Associated With

Discovered By

Charles Best, Healers

Worked alongside Banting through 1921 to isolate and test the extract; excluded from the 1923 Nobel Prize, which Banting split with him in protest.

Led the University of Toronto team; shared the 1923 Nobel Prize with Macleod.

Treats

Insulin therapy manages blood glucose levels; it is not a cure. Frederick Banting and Charles Best's 1921 to 1922 isolation of insulin at the University of Toronto is the founding discovery this treatment rests on.

Source A History of MedicineLois N. Magner
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia Foundation
Wikipedia: Insulin (medication)
Wikipedialead
Quote, lead
As a medication, insulin is any pharmaceutical preparation of the protein hormone insulin that is used to treat high blood glucose.
View the Source
Wikipedia: Insulin (medication)
WikipediaHistory
Quote, History
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.
View the Source
The Greatest Benefit to Mankind: A Medical History of Humanity
Roy Porter, W. W. Norton and Company, 1997Discovered By: Frederick Banting
The Greatest Benefit to Mankind: A Medical History of Humanity
Roy Porter, W. W. Norton and Company, 1997Discovered By: Charles Best
A History of Medicine
Lois N. Magner, CRC PressTreats: Diabetes Mellitus
Our History (Endocrine Society)
Endocrine SocietyAssociated With: EndocrinologyView the Source
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