Medicine Atlas

How Healing Is Practiced
Sign In
Text size
100%
Theme
Condition

Chronic Fatigue Syndrome

Diseases of the Nervous System

Chronic fatigue syndrome, also known as myalgic encephalomyelitis, is a complex, long-term illness characterized by profound fatigue that is not relieved by rest and worsens with physical or mental exertion. Other common features include unrefreshing sleep, cognitive difficulties, and post-exertional malaise, in which symptoms intensify after activity. Its underlying cause is not fully understood, and diagnosis rests on a pattern of symptoms after other explanations have been excluded.

Facts
Classification
Body System
Nervous System 1
ICD-10 Chapter
VI: Diseases of the Nervous System 1
Communicable or Non-communicable
Non-Communicable 2
Transmission Route
Non-Transmissible 2
Partially Attested
First Described
1988 3
Initial case definition of CFS dated to 1988; the related term myalgic encephalomyelitis arose from a 1950s outbreak.
Condition Class
Chronic disabling illness 3
Disputed
Prevalence
0.89% globally under the 1994 CDC criteria; 0.17% under stricter criteria 3
Connections

Associated With

Complex multisystem condition with no single owning subspecialty; managed under internal medicine.

Treated By

Source Graded exercise therapy (Wikipedia)
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter VI
Quote, List of chapters, Chapter VI
Diseases of the nervous system
View the Source
2. Wikipedia: Non-communicable disease
Wikipedia
  • Lead section, transmission-route statement (inferred from disease-category)
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
  • Named examples section
    NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source
3. Wikipedia: Myalgic encephalomyelitis/chronic fatigue syndrome
  • Lead section, first sentence
    Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness.
  • History section
    An initial case definition of CFS was outlined in 1988
  • Epidemiology section
    Based on the 1994 CDC diagnostic criteria, the global prevalence rate for CFS is 0.89%. In comparison, estimates using the stricter 1988 CDC criteria or the 2003 Canadian Consensus Criteria for ME/CFS produced a prevalence rate of only 0.17%.
View the Source
Graded exercise therapy (Wikipedia)
Treated By: Graded Exercise Therapy, Lead: treats Chronic Fatigue Syndrome
Quote, Treated By: Graded Exercise Therapy, Lead: treats Chronic Fatigue Syndrome
Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time, intended as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
View the Source
Frequently Asked Questions

How common is chronic fatigue syndrome?

About 0.89 percent under the 1994 CDC criteria, or about 0.17 percent under stricter criteria.

Estimates of chronic fatigue syndrome vary by which diagnostic criteria are used. Under the 1994 CDC criteria, the global prevalence rate is about 0.89 percent, while the stricter 1988 CDC criteria or the 2003 Canadian Consensus Criteria for ME/CFS produce a prevalence rate of only about 0.17 percent.
Comments (0)
No comments yet. Be the first to share a thought.
Reader Challenges (0)
No disputes yet. Spotted an error or a better source? Open the first one.