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Drugs and Medicinal Substances

Epinephrine

Cardiovascular System Agents

Epinephrine, also known as adrenaline, is a medication used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding.

Facts
Drug Class
Adrenergic receptor agonist (sympathomimetic) 1
Mechanism of Action
Nonselective agonist at alpha and beta adrenergic receptors, triggering glycogenolysis, inhibiting insulin secretion, and increasing cardiac output via vasoconstriction and heart rate acceleration. 1
Approved Use
Treats anaphylaxis, cardiac arrest and superficial bleeding. 1
First Approved / Isolated Year
1901 1
Significant Risk
Shakiness, anxiety, sweating, fast heart rate, high blood pressure and occasionally abnormal heart rhythm. 1
Classification
Approval Status
Approved 1
ATC ClassSourced to the subject's own account
C: Cardiovascular System 2
Route of Administration
Intravenous 1
Route of Administration
Intramuscular 1
Route of Administration
Subcutaneous 1
WHO Essential MedicineSourced to the subject's own account
Core List 3
Connections

Associated With

Allergy and Immunology, Medical Specialties

Treats

Anaphylaxis, Conditions

Epinephrine (adrenaline) is the first-line emergency treatment for anaphylaxis.

Source Adrenaline (Wikipedia)
Sources
1. Adrenaline (Wikipedia)
Wikimedia Foundation
  • Lead section
    used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding
  • Infobox, drug class
    Adrenergic receptor agonist; Sympathomimetic
  • Mechanism of action section
    nonselective agonist binding to alpha and beta adrenergic receptors
  • History section
    Jokichi Takamine successfully isolated and purified the hormone in 1901
  • Medical uses section
    common side effects include shakiness, anxiety, sweating, fast heart rate, high blood pressure
  • Regulatory approval status
  • Route of administration
View the Source
2. Anatomical Therapeutic Chemical Classification System (Wikipedia)
WikipediaFirst-level anatomical group codes, Code C
Quote, First-level anatomical group codes, Code C
Cardiovascular system
View the Source
3. WHO Model List of Essential Medicines (Wikipedia)
WikipediaWHO Model List of Essential Medicines, Antiasthmatic medicines and medicines for chronic obstructive pulmonary disease section
Quote, WHO Model List of Essential Medicines, Antiasthmatic medicines and medicines for chronic obstructive pulmonary disease section
Epinephrine (adrenaline)
View the Source
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