Amyotrophic lateral sclerosis, also known as motor neuron disease or Lou Gehrig's disease, is a rare and ultimately fatal neurodegenerative disease defined by the progressive loss of the nerve cells that control voluntary muscle movement. It is the most common of the motor neuron diseases and typically begins with gradual muscle stiffness, twitching, and weakness that worsens over time as more motor neurons are lost. The disease eventually impairs the muscles needed for movement, speech, swallowing, and breathing.
Facts
Classification
ICD-10 ChapterVI: Diseases of the Nervous System 1 Communicable or Non-communicable Transmission Route Causative Agent
Causative Agent (category) Causative Agent (category)Idiopathic / Multifactorial 3 First Described Connections
Associated With
Source Neuroscience (Wikipedia)
Discovered By
Jean-Martin Charcot's 1869 clinical and pathological description first characterized the disease, historically also called Charcot's disease.
Treated By
Physical therapy is standard supportive care to maintain function in amyotrophic lateral sclerosis.
Sources
1. Wikipedia: ICD-10
WikipediaList of chapters, Chapter VIQuote, List of chapters, Chapter VI
Diseases of the nervous system
View the Source 2. Wikipedia: Non-communicable disease
WikipediaLead section, transmission-route statement (inferred from disease-category)
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
Named examples section
NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others.
View the Source 3. ALS (Wikipedia)
infobox causesQuote, infobox causes
causes: Unknown (90% to 95%) or genetic (5% to 10%)
View the Source 4. Amyotrophic lateral sclerosis (Wikipedia)
Descriptions date back to at least 1824 by Charles Bell, article introView the Source Wikidata: Amyotrophic Lateral Sclerosis
Wikidata Q206901, class allow-list match (w-wdresolver-0926)View the Source Neuroscience (Wikipedia)
Associated With: Neuroscience, Clinical neuroscience sectionQuote, Associated With: Neuroscience, Clinical neuroscience section
Neurology works with diseases of the central and peripheral nervous systems, such as amyotrophic lateral sclerosis (ALS) and stroke, and their medical treatment.
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